CFTR相关论文
目的:囊性纤维化跨膜电导调节因子(cystic fibrosis transmembrane conductance regulator,CFTR)的功能障碍在囊性纤维化(cystic fibr......
牦牛(Bos grunnien)作为一种高原特有牛种,在我国的分布范围主要是以青藏高原为中心及其毗邻的高山、亚高山地区,对海拔3000米以上......
The CFTR polymorphisms poly-T, TG-repeats and M470V in Chinese males with congenital bilateral absen
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目的 支气管扩张(简称支扩)是一种病因各异的慢性炎症性气道疾病,其中囊性纤维化(CF)是欧美白种人发生支扩的常见原因,既往认为CF在......
Glycosylation is one of the most common protein post-translational modifications and plays an important role in protein ......
The N505 residue is important for maintaining normal protein processing of the cystic fibrosis trans
Cystic fibrosis(CF)is caused by genetic mutations that disrupt function of the cystic fibrosis transmembrane conductance......
Cystic Fibrosis Transmembrane Conductance Regulator(CFTR)prevents apoptosis induced by hydrogen pero
Cystic fibrosis transmembrane conductance regulator (CFTR) acts as a cAMP-dependent chloride channel,has been studied in......
目的 研究原发性不育和/或输精管缺如患病群体CFTR基因单倍体Poly-T,TG-repeats和M470V的分布以及相关致病突变,并与正常人进行比......
It has been found in our laboratory that the concentration of chloride ion in airway epithelial cells is elevated by ozo......
Cystic fibrosis(CF),one of the most common inherited disease in the Caucasian population,is caused by mutations of the C......
Malfunction of the cystic fibrosis transmembrane conductance regulator (CFTR) leads to cystic fibrosis, but the regulati......
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Cystic fibrosis is an autosomal recessive disease caused by mutations of the gene encoding the cystic fibrosis transmemb......
Based on systematic review and meta-analysis,the risk for developing cancers in patients with cystic fibrosis(CF)is know......
目的:探讨长链非编码RNA(long non-coding RNA,LncRNA)AC000061.1调节n CFTR基因表达在非梗阻性无精子症(nonobstructive azoospe......
生殖过程是一个细微而复杂的过程,至今人们对此过程尚未十分了解。在生殖过程中,人们对激素变化、胚胎发育等做了深入的探索,但是......
AIM: To investigate the long-term follow-up of distal intestinal obstruction syndrome(DIOS) in Israeli cystic fibrosis(C......
Identification of Herbal Compound Imperatorin with Adverse Effects on ANO1 and CFTR Chloride Channel
Calcium-activated chloride channels(CaCCs) are the crucial regulators of transepithelial fluid secretion, smooth muscle ......
囊性纤维化(CF)是一种主要累及胰腺、肠道。肺、汗腺导管及血管输送的外分泌腺疾病。目前认为,囊性纤维化跨膜传导调节器(CFTR)基因是有......
目的观察续断种子方对无精子症模型小鼠睾丸精子发生发育过程中c-kit/CFTR表达的影响,探索中药干预睾丸生精功能的影响。方法按照......
芬太尼鼻喷剂Lazanda在美国获准上市[关键词]Lazanda;芬太尼;鼻喷剂;癌痛[中图分类号]R 971.1近期美国FDA批准了Archimedes Pharma......
AIM To investigate the pharmacological effect of Tong XieYao Fang(TXYF) formula, a Chinese herbal formula, on Diarrhea-p......
Cystic fibrosis, a common autosomal recessive genetic disorder among Caucasians, is caused by defects in the transmembra......
To determine the genotype of a triplet resulted from an IVF procedure, with discordant cystic fibrosis (CF) phenotype. M......
有一项小鼠的研究提示,在肺中一种称为神经酰胺的脂肪化合物的蓄积会引起慢性肺囊性纤维化感染.该发现对于这种遗传性疾病尚未解决......
目的对已在有关胰腺文献有记载的存在于呼吸道的囊性纤维化跨膜传导调节因子(CFTR)基因类型进行评估。材料与方法本研究经伦理委员......
The susceptibility of T5-TG12 of theCFTR gene in chronic bronchitis occurrence in a Chinese populati
Mutations in the cystic fibrosis transmembrane conductance regulator(CFTR) gene have been implicated in the onset of cys......
来自于英国Cardiff威尔士大学医学院的Robert L.Dormer教授近日报道说,研究表明西地那非(sildenafil,SF)有可能通过纠正突变囊性纤......
目的:探讨辛伐他汀对急性肺损伤大鼠囊性纤维化跨膜传导调节体(CFTR氯离子通道)的影响及其对减轻急性肺损伤的作用。方法:40只雄性......
囊性纤维化跨膜转导调节因子(cystic fibrosis transmembrane conductance regulator,CFTR)是囊性纤维化(CF,cystic fibrosis)基因......
In comparison to cation (K~+,Na~+,and Ca~(2+)) channels,much less is currentlyknown about the functional role of anion ......
囊性纤维化(CF)是一种严重威胁生命的遗传性疾病,目前全球约有7万患者,其平均寿命仅约为38岁。该病由CF跨膜传导调节蛋白(CFTR)缺......
<正>A major breakthrough in understanding diabetes mellitus,especially in the disease cystic fibrosis(CF)was made recent......
ABC转运体(ATP Binding Cassettee Transporters)是一类分布较广、数目众多的跨膜转运体系。ABC乃是ATP-Binding-Cassettee3个字......
Since 2003, China has carried out the pilot of collective forest tenure reform (CFTR). Inrecent years, there have been l......
囊性纤维变性是由囊性纤维变性透膜调节基因(CFTR)变异引起的遗传性疾病 ,目前尚无特殊治疗方法。由于上颌窦粘膜上皮特性和下呼吸......
目的 研究和比较了长春和南京两个不同地区健康人群中囊性纤维化跨膜调节因子(CFTR)基因的多态性,并进一步探讨了中国健康人群中CF......
囊性纤维化(cystic fibrosis)是一种遗传性疾病,由于编码囊性纤维化跨膜传导调节因子(CFTR)的基因突变导致,CFTR负责调控肺泡上皮......
多囊卵巢综合征(PCOS)是女性不孕常见的原因之一,也是育龄期妇女常见的一种复杂的内分泌及代谢异常所致的疾病,通常以排卵障碍或不......
CFTR(Cystic Fibrosis Transmembrane Regulator)是一种c AMP依赖的氯离子通道,在多种上皮组织、心脏、平滑肌、神经元、内皮细胞、......
目的:结直肠癌是严重危害人类健康的消化道恶性肿瘤,其发病率和死亡率都高居全世界恶性肿瘤的前三位。研究表明,DNA启动子异常甲基......
目的:观察龟鹿二仙膏对少弱精子症大鼠的改善作用以及睾丸囊性纤维化跨膜传导调节因子(CFTR)蛋白表达的影响。方法:将50只雄性SD大......
一、选择题(6小题,共计48分) 1. 关于“中心法则”含义的叙述正确的选项是( ) A. DNA只能来自DNA的复制 B. 中心法则只能适用......
三年前,科学工作者找到了导致囊性纤维变性的(CF)缺陷蛋白质,它使患此病的人体内产生一层厚的粘液持续损伤肺和其它器官,导致早死......
Bar Harbor消息:一般认为只能引起囊性纤维变性(CF)的CFTR基因,突变能导致其他的疾病,其中包括慢性肺炎和肺动脉窦的疾病。囊性纤......
两项新的研究报道,在自发性慢性胰腺炎与囊性纤维变性跨膜调节器(CFTR)基因突变之间存在密切的联系。美国达勒姆市杜克医学中心的......